Here at BioReset, when a patient comes in seeking relief from their chronic nerve pain, we ask a myriad of questions to better understand their condition. Recently, we have noticed an undeniable pattern amongst those who experience neuropathy; when asked, “Are you taking a cholesterol lowering statin drug?”, a staggering number of patients reply with “Yes, actually. I am.”

Over the past decade, numerous studies have emerged linking the use of statins to coenzyme Q10 depletion. Co-Q10 is an enzyme that naturally occurs in the body and is a critical component in the production of ATP, which is known as the body’s “fuel” and the key to energy metabolism, mitochondrial health and our vitality. Without CoQ10, ATP, and optimally functioning mitochondria, the body is left without the energy to sustain a wide range of biological functions. CoQ10 also acts as an antioxidant in the body, fighting free radicals and preventing oxidative damage and stress, which is critical in preventing immune and inflammatory conditions related to aging, lifestyle choices or environmental exposures. CoQ10 is biosynthesized through the same pathway as cholesterol, therefore when a cholesterol reducing statin drug blocks the mevalonate pathway, it also blocks the production of coenzyme Q10, ultimately leading to a deficiency. Because CoQ10 deficiency can lead to a systemic shortage of energy, the symptoms of the deficiency can manifest in a number of ways, but the most common are profound fatigue, muscle pain and weakness, neuropathy and nerve pain. It is no coincidence that these are the same “side effects” listed for statins; the depletion of CoQ10 when on statin drugs can lead to a shortage of energy for nerve cells and heart muscle cells, as well as a shortage of ATP needed for muscle recovery and repair. The result is often expedited degeneration, myopathy, and neuropathic pain.

 The good news is that at BioReset, we believe in regeneration. In addition to addressing localized nerve pain with nerve hydrodissection, we also offer two intravenous treatments for regeneration and repair: IV CoQ10 and IV NAD. Both intravenous therapies support mitochondrial health, since both are integral components to energy metabolism. Much like CoQ10, NAD [hyperlink to NAD page or NAD blog] is a key component in the production of ATP (fuel for our body), given that it is responsible for transporting electrons derived from the metabolism of fat and sugars to generate ATP and support optimal mitochondrial function. When we administer both CoQ10 and NAD intravenously, it allows the body to replenish its depleted stores and begin to have the energy to repair inflammation, dysfunction, and damage, and patients finally experience the capacity to heal. We’ve seen long term chronic nerve pain resolve, and patients begin to feel as though their energy and vitality is restored. With these treatments, not only do our patients experience relief from pain, but they often express that they feel as though an internal switch has been flipped, as though the lights have been turned back on after living life for so long in the dark. If you’re looking for support in reversing your statin-related nerve pain, drug-related myopathy or profound chronic fatigue, please reach out to us to talk about your options and the hope that exists for brighter days.